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Crospon and Medical Measurement Systems Sign World-Wide Distribution Deal

Medical Measurement Systems to distribute EndoFLIP® product to EMEA countries.

First Shipment to European Market in June

Friday 29th May 2009 – Crospon, a medical device developer based in Galway, Ireland, today
announced it has agreed a worldwide distribution deal for its flagship gastroenterology product,
EndoFLIP®. The agreement with Dutch company, Medical Measurement Systems, one of the
world’s leading companies in the development and distribution of medical gastrodiagnostic
systems will result in first customer shipments into Europe during the month of June.
Crospon develops leading edge minimally invasive medical devices for monitoring, diagnosis and
therapy in the gastroenterology area.

The EndoFLIP® tool which is pending FDA approval was designed by Crospon to provide a more
physiologically relevant diagnostic test for gastroesophageal reflux disease (GERD). Chronic
GERD is a prevalent disorder reaching epidemic proportions worldwide that manifests itself as
severe heartburn caused by stomach acid refluxing up into the oesophagus.
Crospon’s development of the EndoFLIP® system was recently recognised with the 2009
European Gastroenterology Technology Implementation of the Year Award by Frost & Sullivan.
Announcing the distribution agreement, John O’Dea, CEO, Crospon said, “Today’s
announcement is another significant step in the development of both Crospon and EndoFLIP®.
The international reach which will be provided by Medical Measurement Systems will be crucial
to the successful rollout of the EndoFLIP® product and we look forward to working with them in
the months and years ahead.”

Expanding, O’Dea said, “The pace of Crospon’s growth over the last six months has accelerated.
The establishment of our US operation, CE Mark certification and the recent recognition from
Frost & Sullivan means that we are well placed for the challenges of going to market.”
Located in Enschede, a major industrial city in the Netherlands, Medical Measurement Systems
distribution network spans across 60 countries and during the first six months distribution of the
EndoFLIP® tool will be particularly targeted towards Gastroenterologists in the EMEA area.
Commenting on the announcement, Arjen de Weerd, CEO, Medical Measurement Systems said,
“EndoFLIP® is a very promising new product for medical professionals to actually see and
therefore better diagnose the function of the Lower Esophageal Sphincter (LES). EndoFLIP® fits
perfectly in our complete range of GI measurement systems to diagnose gastro-esophageal
reflux disease (GERD) and motility disorders.”

In January, Crospon announced that its EndoFLIP® system had received CE Mark certification
from the NSAI (National Standards Authority of Ireland), the Irish notified body in accordance
with the European Medical Device Directive. The Company also announced the appointment of Larry Fulton as Vice President of Sales –Americas located at the Crospon’s newly established US
operation in Carlsbad, California.

Crospon will be exhibiting the EndoFLIP® system at Digestive Disease Week in Chicago,
Illinois at the end of May.

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EndoFLIP logo   Crospon Inc. 701 Palomar Airport Rd, Carlsbad, CA 92011, USA. Phone: 1-855-CROSPON
Crospon Ireland. Galway Business Park, Dangan, Galway, Ireland Phone: +353-91-519880