Crospon logo

About Us
Product Brochures
EndoFLIP® Technology

Clinical Applications

- Upper GI Surgery

- Bariatric Surgery

- Upper GI Imaging

- Cardiology

- Therapeutic Endoscopy

- Colorectal Imaging

Contact Us



Two new EndoFLIP papers published on POEM and EoE

5th March 2013

This week two new EndoFLIP papers have been published. The first paper Effect of peroral endoscopic myotomy on esophagogastric junction physiology in patients with achalasia demonstrates that POEM provides improved GEJ distensibility, as measured with the EndoFLIP system. Equally, the authors highlight that increasing the distensibility of the junction increases the risk of reflux esophagitis. This highlights the need to titrate the degree of opening of the GEJ achieved during the POEM procedure i.e. so that it is open enough to relieve dysphagia and not too open as to increase the risk of esophagitis.  This, and other work by the same authors, suggests that a distensibility target of 2.9 mm2/mmHg  seems appropriate. The second paper Functional luminal imaging probe topography: an improved method for characterizing esophageal distensibility in eosinophilic esophagitis follows on from previous work by the same authors describing the use of EndoFLIP to provide a biomarker for symptom resolution from EoE. With the growing prevalence of the disorder, along with increased interest in pharmaceutical therapies, there is a need for more rigorous biomarkers to track symptom resolution,  and the authors are at the forefront of developing algorithms employing EndoFLIP to assess mural distensibility as one such biomarker.


Newsroom Links
News Headlines
Upcoming Events
EndoFLIP logo   Crospon (USA) 701 Palomar Airport Rd, Carlsbad, CA 92011, USA. Phone: 1-855-CROSPON
Crospon (EU) Galway Business Park, Dangan, Galway, H91 P2DK, Ireland. Phone +353-91-519880