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8 new papers utilizing EndoFLIP Technology published from February 2016 to August 2016

9th September 2016

Eight new papers have been recently published which describe different uses of EndoFLIP technology, three in surgery and 5 five in the gastrodiagnostics area.

Intraoperative Assessment of Esophagogastric Junction Distensibility During Laparoscopic Heller Myotomy compared distensibility of the GEJ after Toupet and Nissen fundoplication in a 75 patient study and found that the Toupet wrap is approximately 30% looser than a Nissen wrap. Intraoperative assessment of the effects of laparoscopic sleeve gastrectomy on the distensibility of the lower esophageal sphincter using impedance planimetry studied the impact of sleeve gastrectomy on GEJ distensibility in a single center 15 patient study. Surgical Management of Esophageal Achalasia: Evolution of an Institutional Approach to Minimally Invasive Repair discusses an minimally invasive surgical approach to achalasia surgery in children, an element of which comprises the use of EndoFLIP. Severity of endoscopically identified esophageal rings correlates with reduced esophageal distensibility in eosinophilic esophagitis presents the use of EndoFLIP in a 72 patient study, to assess distensibility of rings in eosinophilic esophagitis to help better understand the severity of esophageal remodeling and thus help stratify the risk for food impaction. Eosiniphilic esophagitis is a relatively new diagnostic area for EndoFLIP which will entail the development of more specialist diagnostic algorithms. This topic is discussed in depth in Evaluation of esophageal distensibility in eosinophilic esophagitis: an update and comparison of functional lumen imaging probe analytical methods. Esophagogastric junction distensibility identifies achalasia subgroup with manometrically normal esophagogastric junction relaxation, in a 13 patient study, demonstrates that there exists a sub-group of patients having achalasia that may not be detected using normal manometry classification criteria. Having detected achalasia using an EndoFLIP distensibility measurement, these patients respond favorably to achalasia treatment. Comparison of videofluoroscopy and impedance planimetry for the evaluation of oesophageal stenosis: a retrospective study concluded in a 56 patient study that videofluoroscopy and impedance planimetry correlate significantly regarding tablet impaction and residual oesophageal lumen. Finally, a 10 patient study, Increased yield pressure in the anal canal during sacral nerve stimulation: a pilot study with the functional lumen imaging probe, demonstrates how distensibility is a useful measure in assessing the performance of sacral nerve stimulation in fecal incontinence patients.

The references for these eight papers may be found below.

Esophagogastric junction distensibility is greater following Toupet compared to Nissen fundoplication.
DeHaan RK, Davila D, Frelich MJ, Gould JC.
Surg Endosc. 2016 Apr 29. [Epub ahead of print]

Intraoperative assessment of the effects of laparoscopic sleeve gastrectomy on the distensibility of the lower esophageal sphincter using impedance planimetry.
Reynolds JL, Zehetner J, Shiraga S, Lipham JC, Katkhouda N.
Surg Endosc. 2016 Apr 12. [Epub ahead of print]

Surgical Management of Esophageal Achalasia: Evolution of an Institutional Approach to Minimally Invasive Repair.
Petrosyan M, Khalafallah A, Guzzetta P, Sandler A, Darbari A, Kane T.
Journal of Pediatric Surgery (2016), doi: 10.1016/j.jpedsurg.2016.05.015 [Epub ahead of print]

Severity of endoscopically identified esophageal rings correlates with reduced esophageal distensibility in eosinophilic esophagitis.
Chen JW, Pandolfino JE, Lin Z, Ciolino JD, Gonsalves N, Kahrilas PJ, Hirano I.
Endoscopy. 2016 May 20;48:794-801

Evaluation of esophageal distensibility in eosinophilic esophagitis: an update and comparison of functional lumen imaging probe analytical methods.
Carlson DA, Lin Z, Hirano I, Gonsalves N, Zalewski A, Pandolfino JE.
Neurogastroenterol Motil. 2016 Jun 16. doi: 10.1111/nmo.12888. [Epub ahead of print]

Esophagogastric junction distensibility identifies achalasia subgroup with manometrically normal esophagogastric junction relaxation.
Ponds FA, Bredenoord AJ, Kessing BF, Smout AJ
Neurogastroenterol Motil. 2016 Jul 25. doi: 10.1111/nmo.12908. [Epub ahead of print]

Comparison of videofluoroscopy and impedance planimetry for the evaluation of oesophageal stenosis: a retrospective study.
Scharitzer M, Lenglinger J, Schima W, Weber M, Ringhofer C, Pokieser P.
Eur Radiol. 2016 Aug 23. [Epub ahead of print]

Increased yield pressure in the anal canal during sacral nerve stimulation: a pilot study with the functional lumen imaging probe.
Haas S, Liao D, Gregersen H, Lundby L, Laurberg S, Krogh K.
Neurogastroenterol Motil. 2016 Aug 21. doi: 10.1111/nmo.12929. [Epub ahead of print]

 
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